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  2. Leuprorelin - Wikipedia

    en.wikipedia.org/wiki/Leuprorelin

    Lupron injection was approved by the FDA for treatment of advanced prostate cancer on 9 April 1985. [ 45 ] [ 4 ] [ 43 ] [ 44 ] Lupron depot for monthly intramuscular injection was approved by the FDA for palliative treatment of advanced prostate cancer on 26 January 1989.

  3. Depot injection - Wikipedia

    en.wikipedia.org/wiki/Depot_injection

    Depot injections can be created by modifying the drug molecule itself, as in the case of prodrugs, or by modifying the way it is administered, as in the case of oil/lipid suspensions. Depot injections can have a duration of action of one month or greater and are available for many types of drugs, including antipsychotics and hormones.

  4. Feminizing hormone therapy - Wikipedia

    en.wikipedia.org/wiki/Feminizing_hormone_therapy

    GnRH agonists, such as leuprorelin (Lupron), goserelin (Zoladex), and buserelin (Suprefact), are GnRH receptor superagonists, and work by producing profound desensitization of the GnRH receptor such that the receptor becomes non-functional.

  5. Gonadotropin-releasing hormone agonist - Wikipedia

    en.wikipedia.org/wiki/Gonadotropin-releasing...

    A gonadotropin-releasing hormone agonist (GnRH agonist) is a type of medication which affects gonadotropins and sex hormones. [1] They are used for a variety of indications including in fertility medicine and to lower sex hormone levels in the treatment of hormone-sensitive cancers such as prostate cancer and breast cancer, certain gynecological disorders like heavy periods and endometriosis ...

  6. What does it mean to commute an execution? Here's what to ...

    www.aol.com/news/does-mean-commute-execution...

    What does it mean to commute a sentence? A sentence commutation reduces the severity of the sentence. Under Article II, Section 2 of the Constitution, ...

  7. Pregnant meteorologist responds after being criticized for ...

    www.aol.com/news/pregnant-meteorologist-responds...

    A meteorologist from Seattle, Washington, who is nearly eight months pregnant, has a message for viewers who feel the need to comment on her clothing choices.

  8. Consulting firm McKinsey to pay $650 million to resolve US ...

    www.aol.com/news/consulting-firm-mckinsey-pay...

    BOSTON (Reuters) -McKinsey & Co has agreed to pay $650 million to resolve a U.S. Department of Justice investigation into the consulting firm's work advising opioid manufacturer OxyContin maker ...

  9. Medroxyprogesterone acetate - Wikipedia

    en.wikipedia.org/wiki/Medroxyprogesterone_acetate

    Medroxyprogesterone acetate (MPA), also known as depot medroxyprogesterone acetate (DMPA) in injectable form and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. [10] [4] It is used as a method of birth control and as a part of menopausal hormone therapy.

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