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As of November 2015, there are a number of ongoing and recently completed clinical trials of novel targeted agents for HER2+ metastatic breast cancer, e.g. margetuximab. [36] Additionally, NeuVax (Galena Biopharma) is a peptide-based immunotherapy that directs "killer" T cells to target and destroy cancer cells that express HER2. It has entered ...
Ann Marie Rogers (1952 – 2 March 2009) was a British campaigner who fought a successful landmark court battle to receive the breast cancer drug Herceptin on the NHS. [1] Herceptin (Trastuzumab) is a treatment for women with breast cancer whose tumors have too much HER2 protein. This type of cancer is known as "HER2-positive", "HER2+", or ...
The film follows the true story of Dr. Dennis Slamon (played by Harry Connick Jr.), who helped develop the breast cancer drug Herceptin, over the course of 8 years from 1988 to 1996. Dr. Dr. Slamon is a physician scientist at UCLA Medical Center ( Los Angeles ), where he has developed the experimental drug Herceptin, which he believes will ...
Dennis Joseph Slamon (born August 6, 1948), [1] [2] is an American oncologist and chief of the division of Hematology-Oncology at UCLA.He is best known for his work identifying the HER2/neu oncogene that is amplified in 25–33% of breast cancer patients and the resulting treatment trastuzumab.
In early-stage HER2-positive breast cancer, trastuzumab-containing regimens improved overall survival (Hazard ratio (HR) = 0.66) and disease-free survival (HR = 0.60). [39] Increased risk of heart failure (RR = 5.11) and decline in left ventricular ejection fraction ( relative risk RR = 1.83) were seen in these trials as well. [ 39 ]
Sally's breast cancer story. Two years after Flynn's diagnosis, her younger sister Sally Peterson learned that she also had breast cancer. “I was 43. It was shocking and devastating. I had three ...
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