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These factors interact to create a threshold for the development of mental disorders. The types of coping and defense mechanisms used can either contribute to vulnerability or act as protective factors. [37] Coping and defence mechanisms work in tandem to balance out feelings of anxiety or guilt, categorizing them both as a "mechanisms of ...
This has provided key insights on the underlying mechanisms of addiction, including substance use and non-substance (behavioral) addictions. [15] Addiction hijacks the brain’s reward system, which normally encourages individuals to engage in survival-related activities such as socializing, eating, or achieving goals. Substances or specific ...
The hijack model of substance addiction suggests that Psychoactive drugs act on ancient and evolutionarily conserved neural mechanisms associated with positive emotions that evolved to mediate incentive behavior. [1] [2] They induce emotions that in human evolutionary history signaled a benefit for the group. Modern drugs tap into these ...
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...
The common biomolecular mechanisms underlying addiction – CREB and ΔFosB – were reviewed by Eric J. Nestler in a 2013 review. [3] Genetics and mental disorders may precipitate the severity of a drug addiction. It is estimated that 50% of healthy individuals developing an addiction can trace the cause to genetic factors. [4]
Moreover, affect is implicated in a range of concepts relevant to addiction: positive reinforcement, behaviour motivation, regulation of cognition and mood, and reasoning and decision making. [ 8 ] [ 9 ] Emotion-motivated reasoning has been shown to influence addictive behaviours via selecting outcomes that minimize negative affective states ...
It was originated and advocated by Stanton Peele in his book The Truth About Addiction and Recovery (with Archie Brodsky and Mary Arnold, 1991). Proponents of the life-process model argue that unitary biological mechanisms cannot account for addictive behavior and thus do not support using the term disease. They instead emphasize the individual ...
In addiction, epigenetic mechanisms play a central role in the pathophysiology of the disease; [2] it has been noted that some of the alterations to the epigenome which arise through chronic exposure to addictive stimuli during an addiction can be transmitted across generations, in turn affecting the behavior of one's children (e.g., the child ...