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A systematic review published in the journal Obesity Reviews in 2019 found that just about all of the widely-used medications for depression resulted in long-term weight gain, with the exception ...
Long-term efficacy remains poorly characterized. Similar recommendations apply to binge eating disorder. [37] SSRIs provide short-term reductions in binge eating behavior, but have not been associated with significant weight loss. [38] Clinical trials have generated mostly negative results for the use of SSRIs in the treatment of anorexia ...
Experts agree that eating wholesome, healthy meals, reducing calories, and increasing physical activity are the best ways to lose weight and keep it off long-term. Still, many people turn to ...
With time, fluoxetine and norfluoxetine inhibit their own metabolism, so fluoxetine elimination half-life increases from 1 to 3 days, after a single dose, to 4 to 6 days, after long-term use. [9] Similarly, the half-life of norfluoxetine is longer (16 days) after long-term use.
Research shows that up to 60% of the weight loss from prescription medications may come from lean body mass. Muscle loss can affect strength and mobility, so eating enough protein to preserve lean ...
There is a gradual weight regain after the first year of about 1 to 2 kg per year, but on the long-term this still results in weight loss. [4] Risk factors for cardiovascular disease and for diabetes are reduced for several years after taking part in a weight management programme, even if people regained weight.
Also, currently available antidepressants all elicit undesirable side-effects, and new agents should be divested of the distressing side-effects of both first and second-generation antidepressants. [6] Another serious drawback of all antidepressants is the requirement for long-term administration prior to maximal therapeutic efficacy.
At six months, Lexapro, Paxil and Cymbalta users were 10% to 15% more likely to gain at least 5% of their starting weight than Zoloft consumers. Prozac was not associated with a six-month weight ...
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