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Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [ 4 ] [ 5 ] [ 6 ] It is either used at low doses for chronic illnesses or used at high doses during acute flares.
Methylprednisolone succinate, sold under the brand name Solu-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 succinate ester of methylprednisolone—which is used by intravenous administration.
[1] [4] [5] Methylprednisolone acetate was previously suspended with polyethylene glycol but is no longer formulated with this excipient due to concerns about possible toxicity. [6] [8] Depo methylprednisolone acetate is a depot injection and is absorbed slowly with a duration of weeks to months with a single intramuscular injection. [5]
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25 mg of hydrocortisone every eight hours for 24 hours. Resume usual dose thereafter. Major surgical stress (eg, esophagogastrectomy, total proctocolectomy, open heart surgery) 100 mg hydrocortisone IV: 50 mg every eight hours for 24 hours. Taper dose by half per day to maintenance level.
5–20 mg/day Metandienone b: Dianabol: Tablet: 5–15 mg/day Mesterolone b: Proviron: Tablet: 25–150 mg/day Sublingual: Testosterone b: Testoral: Tablet: 5–10 mg 1–4×/day Methyltestosterone b: Metandren, Oreton Methyl: Tablet: 10–30 mg/day Buccal: Testosterone: Striant: Tablet: 30 mg 2×/day Methyltestosterone b: Metandren, Oreton ...
[7] [8] [6] It differs from the similarly named prednisone in having a hydroxyl at the 11th carbon instead of a ketone. Common side effects with short-term use include nausea, difficulty concentrating, insomnia, increased appetite, and fatigue. [5] More severe side effects include psychiatric problems, which may occur in about 5% of people. [9]
Download as PDF; Printable version ... μg testosterone per day (6.4 ± 2.0 mg ... of 100 mg/week and by 70% at a dosage of 300 mg/week in men following 6 weeks ...