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When an event occurs which causes the bundle of cilia to deflect toward the taller side, ion channels open, and the inward current causes a depolarization of the cell. This is known as a positive deflection. This process involves the stretching of tip links, which pull the ion channels open.
Deflections of the stereocilia in the direction of the tallest stereocilia leads to an increased rate of opening of nonspecific cation channels. This, in turn, causes receptor depolarization and leads to the excitement of the cochlear nerve afferents that are located at the base of the hair cell. Deflections of the stereocilia in the opposite ...
There are both external causes of damage, including infection, and ototoxic drugs, as well as intrinsic causes, including genetic mutations. A common cause or exacerbating factor in SNHL is prolonged exposure to environmental noise, or noise-induced hearing loss. Exposure to a single very loud noise such as a gun shot or bomb blast can cause ...
The stereocilia in a hair bundle are arranged in multiple rows of different heights. In addition to the stereocilia, a true ciliary structure known as the kinocilium exists and is believed to play a role in hair cell degeneration that is caused by exposure to high frequencies.
In general, structural damages to any anatomical part of the human ear can cause hearing-related problems. Usually, minor bending of the stereocilia of the inner ear is associated with temporary hearing loss and is involved in auditory fatigue. Complete loss of the stereocilia causes permanent hearing damage and is more associated with noise ...
While many causes of lower left abdominal pain can be managed at home through lifestyle changes and over-the-counter remedies, persistent or severe symptoms require professional medical evaluation ...
The hair bundle is composed of stiff microvilli called stereocilia and is involved with mechanoreception of sound waves. Stereocilia cells generate an electrical response to the vibrations of sound waves, crucial for normal hearing. This gene is part of a tandem duplication on chromosome 15; the second copy is a pseudogene.
The main causes of scalp pain. There are a lot of potential culprits behind your scalp pain. These are the most common ones doctors see and diagnose. Tension from hairstyles
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