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  2. mRNA vaccine - Wikipedia

    en.wikipedia.org/wiki/MRNA_vaccine

    Retrovirus can be single-stranded RNA (just as many SARS-CoV-2 vaccines are single-stranded RNA) which enters the cell nucleus and uses reverse transcriptase to make DNA from the RNA in the cell nucleus. A retrovirus has mechanisms to be imported into the nucleus, but other mRNA (such as the vaccine) lack these mechanisms.

  3. DNA vaccine - Wikipedia

    en.wikipedia.org/wiki/DNA_vaccine

    Conventional vaccines contain either specific antigens from a pathogen, or attenuated viruses which stimulate an immune response in the vaccinated organism. DNA vaccines are members of the genetic vaccines, because they contain a genetic information (DNA or RNA) that codes for the cellular production (protein biosynthesis) of an antigen.

  4. Genetic vaccine - Wikipedia

    en.wikipedia.org/wiki/Genetic_vaccine

    In 1995, Robert Conry and colleagues described that a humoral immune response was also elicited after vaccination with an RNA vaccine. [13] [11] While DNA vaccines were more frequently researched in the early years due to their ease of production, low cost, and high stability to degrading enzymes, but sometimes produced low vaccine responses ...

  5. mRNA vaccines: 5 things to know - AOL

    www.aol.com/news/nobel-prize-mrna-vaccines-5...

    Two pioneering scientists who created the technology behind life-saving Covid-19 vaccines have won the Nobel Prize in medicine or physiology.

  6. Here’s what a Nobel Prize-winning scientist wants you ... - AOL

    www.aol.com/nobel-prize-winning-scientist-breaks...

    In his new book “The Catalyst,” Thomas R. Cech talks about the Covid-19 vaccines, what RNA means for future health crises and how gene editing with CRISPR factors in.

  7. RNA therapeutics - Wikipedia

    en.wikipedia.org/wiki/RNA_Therapeutics

    RNA therapeutics are a new class of medications based on ribonucleic acid (RNA). Research has been working on clinical use since the 1990s, with significant success in cancer therapy in the early 2010s. [1] In 2020 and 2021, mRNA vaccines have been developed globally for use in combating the coronavirus disease (COVID-19 pandemic). [2]

  8. Nucleoside-modified messenger RNA - Wikipedia

    en.wikipedia.org/wiki/Nucleoside-modified...

    A nucleoside-modified messenger RNA (modRNA) is a synthetic messenger RNA (mRNA) in which some nucleosides are replaced by other naturally modified nucleosides or by synthetic nucleoside analogues. [ 1 ] modRNA is used to induce the production of a desired protein in certain cells.

  9. Reverse genetics - Wikipedia

    en.wikipedia.org/wiki/Reverse_genetics

    Diagram illustrating the development process of avian flu vaccine by reverse genetics techniques. Reverse genetics is a method in molecular genetics that is used to help understand the function(s) of a gene by analysing the phenotypic effects caused by genetically engineering specific nucleic acid sequences within the gene.

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