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Nurofen is a brand of range of pain-relief medication containing ibuprofen made by the English-Dutch company Reckitt Benckiser. [1] Introduced in 1983, the Nurofen brand was acquired following Reckitt Benckiser's acquisition of Boots healthcare international in 2005 for £1.93 billion, which included Nurofen, Strepsils, and Clearasil. [2]
Example of some 200 mg ibuprofen tablets A 150 ml bottle (100 mg/5 ml dosage) of ibuprofen, sold in Greece. Ibuprofen is used primarily to treat fever (including postvaccination fever), mild to moderate pain (including pain relief after surgery), painful menstruation, osteoarthritis, dental pain, headaches, and pain from kidney stones.
This page was last edited on 6 November 2024, at 03:11 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
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By the late 1980s, Nurofen had a 12% share of the analgesics market. Gold Greenlees Trott (GGT), who later bought BBDP then were bought by Omnicom Group in 1998 and made part of TBWA Worldwide, were commissioned to make an advert to markedly increase Nurofen's market share. Analgesics are mainly purchased by 25- to 40-year-old women.
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The mechanism of action of metamizole is believed to be exerted via its active metabolites, specifically, arachidonoyl-4-methylaminoantipyrine (ARA-4-MAA) and arachidonoyl-4-aminoantipyrine (ARA-4-AA). [39] [19] [24] This mechanism of action has been compared to paracetamol and its active arachidonic acid metabolite AM404.