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  2. Adrenal cortex - Wikipedia

    en.wikipedia.org/wiki/Adrenal_cortex

    The adrenal cortex is the outer region and also the largest part of the adrenal gland. It is divided into three separate zones: zona glomerulosa, zona fasciculata and zona reticularis. Each zone is responsible for producing specific hormones. It is also a secondary site of androgen synthesis. [2]

  3. Adrenal gland - Wikipedia

    en.wikipedia.org/wiki/Adrenal_gland

    The adrenal cortex is the outermost layer of the adrenal gland. Within the cortex are three layers, called "zones". When viewed under a microscope each layer has a distinct appearance, and each has a different function. [13] The adrenal cortex is devoted to production of hormones, namely aldosterone, cortisol, and androgens. [14]

  4. Development of the endocrine system - Wikipedia

    en.wikipedia.org/wiki/Development_of_the...

    The adrenal cortex originates from the thickening of the intermediate mesoderm. [3] At five to six weeks of gestation, the mesonephros differentiates into a tissue known as the gonadal ridge. The gonadal ridge produces the steroidogenic cells for both the gonads and the adrenal cortex. [4] The adrenal medulla is derived from ectodermal cells ...

  5. Adrenocortical hormone - Wikipedia

    en.wikipedia.org/wiki/Adrenocortical_hormone

    In humans and other animals, the adrenocortical hormones are hormones produced by the adrenal cortex, the outer region of the adrenal gland.These polycyclic steroid hormones have a variety of roles that are crucial for the body's response to stress (for example, the fight-or-flight response), and they also regulate other functions in the body.

  6. Zona glomerulosa - Wikipedia

    en.wikipedia.org/wiki/Zona_glomerulosa

    H & E staining of the adrenal cortex. The zona glomerulosa is the outermost layer, below the renal capsule (near the pointer) In response to increased potassium levels, renin or decreased blood flow to the kidneys, cells of the zona glomerulosa produce and secrete the mineralocorticoid aldosterone into the blood as part of the renin ...

  7. Mineralocorticoid - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid

    Hyperaldosteronism (the syndrome caused by elevated aldosterone) is commonly caused by either idiopathic adrenal hyperplasia or by an adrenal adenoma. The two main resulting problems: Hypertension and edema due to excessive Na+ and water retention. Accelerated excretion of potassium ions (K+). With extreme K+ loss there is muscle weakness and ...

  8. Endocrine system - Wikipedia

    en.wikipedia.org/wiki/Endocrine_system

    The genital ridge produces the steroidogenic cells for both the gonads and the adrenal cortex. The adrenal medulla is derived from ectodermal cells. Cells that will become adrenal tissue move retroperitoneally to the upper portion of the mesonephros. At seven weeks of gestation, the adrenal cells are joined by sympathetic cells that originate ...

  9. Zona reticularis - Wikipedia

    en.wikipedia.org/wiki/Zona_reticularis

    Cells in the zona reticularis produce precursor androgens including dehydroepiandrosterone (DHEA) and androstenedione from cholesterol. [2] DHEA is further converted to DHEA-sulfate via a sulfotransferase, SULT2A1. [3] These precursors are not further converted in the adrenal cortex if the cells lack 17β-Hydroxysteroid dehydrogenase.