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Ecgonine (tropane derivative) is a tropane alkaloid found naturally in coca leaves. It has a close structural relation to cocaine: it is both a metabolite and a precursor, and as such, it is a controlled substance in many jurisdictions, as are some substances which can be used as precursors to ecgonine itself.
Cocaine — a tropane alkaloid — is a weakly alkaline compound, and can therefore combine with acidic compounds to form salts. The hydrochloride (HCl) salt of cocaine is by far the most commonly encountered, although the sulfate (SO 4 2− ) and the nitrate (NO 3 − ) salts are occasionally seen.
Methylecgonine, also known as ecgonine methyl ester is a prominent tropane alkaloid found in coca leaves. [1] It is metabolite of cocaine, [2] and may be used as a precursor for it. It also occurs as minor alkaloid in roots of many Datura species such as Datura stramonium [3] and Datura innoxia. [4]
Of the approximately 200 members in the genus Erythroxylum, most species contain the central nervous system stimulant tropane alkaloid, known more commonly as cocaine.Because the plant is endemic ...
Chemical structure of tropane which forms the core of tropane alkaloids Chemical structure and phylogeny of tropane alkaloids. Displayed are 3 chemical compounds that occur as natural products in 5 plant species. Tropane alkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical ...
The study — which included about 400 patients randomized to receive the treatment or a placebo — found that about 14% of participants who got the combination treatment consistently tested ...
Methylecgonine cinnamate is a natural tropane alkaloid found within the coca plant. [1] Its more common name, cinnamoylcocaine, reflects its close structural similarity to cocaine. It is pharmacologically inactive, [2] but some studies funded by anti-drug agencies imply that it is active when smoked.
RTI(-4229)-113 (2β-carbophenoxy-3β-(4-chlorophenyl)tropane) is a stimulant drug which acts as a potent and fully selective dopamine reuptake inhibitor (DRI). It has been suggested as a possible substitute drug for the treatment of cocaine addiction .