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Drug rehabilitation is the process of medical or psychotherapeutic treatment for dependency on psychoactive substances such as alcohol, prescription drugs, and street drugs such as cannabis, cocaine, heroin, and amphetamines.
Cocaine is a relatively "balanced" inhibitor, although facilitation of dopaminergic neurotransmission is what has been linked to the reinforcing and addictive effects. In addition, cocaine has some serious limitations in terms of its cardiotoxicity [188] due to its local anesthetic activity. Thousands of cocaine users are admitted to emergency ...
The duration of abstinence increased from an average of 32 days before treatment to 217.2 days during treatment. This suggests that coca leaf infusion plus counseling may be effective at preventing relapse during cocaine addiction treatment. [139] There is little information on the pharmacological and toxicological effects of consuming coca tea.
An experimental cocaine vaccine may help addicts end their addictions by inhibiting the drug's effects on the brain -- that is, preventing the high -- according to a National Institute on Drug ...
Treatment options include psychotherapy and psychopharmacotherapy (i.e., medications) or a combination of both. Cognitive behavioral therapy (CBT) is the most common form of psychotherapy used in treating behavioral addictions; it focuses on identifying patterns that trigger compulsive behavior and making lifestyle changes to promote healthier ...
Cocaine dependence is a neurological disorder that is characterized by withdrawal symptoms upon cessation from cocaine use. [1] It also often coincides with cocaine addiction which is a biopsychosocial disorder characterized by persistent use of cocaine and/or crack despite substantial harm and adverse consequences.
These can be regulated by chronic cocaine treatment via D1 receptors, and all of the genes contain AP-1 transcriptional complex binding sites in their promoter regions. For extracellular signaling molecules, they looked at the expression of the genes IGFBP6 and SDF1. Both of these were induced in the caudate putamen in wild-type mice but ...
Calixcoca, unlike other anti-cocaine vaccines, is not protein-based. [2] The material that forms the basis of the vaccine is the V4N2 molecule. [ 4 ] This molecule stimulates the immune system to produce antibodies that bind to cocaine molecules in the blood.