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The number of pseudogenes in the human genome is on the order of 13,000, [27] and in some chromosomes is nearly the same as the number of functional protein-coding genes. Gene duplication is a major mechanism through which new genetic material is generated during molecular evolution .
•List of human protein-coding genes page 2 covers genes EPHA1–MTMR3 •List of human protein-coding genes page 3 covers genes MTMR4–SLC17A7 •List of human protein-coding genes page 4 covers genes SLC17A8–ZZZ3 NB: Each list page contains 5000 human protein-coding genes, sorted alphanumerically by the HGNC-approved gene symbol.
Along with identifying all of the approximately 20,000–25,000 genes in the human genome (estimated at between 80,000 and 140,000 at the start of the project), the Human Genome Project also sought to address the ethical, legal, and social issues that were created by the onset of the project. [85]
The following are some of the gene count estimates of human chromosome 18. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction).
Genome size Number of chromosomes Number of genes predicted Organization Year of completion Arabidopsis thaliana Ecotype:Columbia: Wild mustard Thale Cress Model plant 135 Mb [10] 5 25,498, [11] 27,400, [12] 31,670 (UniProt) Arabidopsis Genome Initiative [13] 2000 [11] Cyanidioschyzon merolae Strain:10D: Red algae: Simple eukaryote: 16.5 Mb 20 ...
The following are some of the gene count estimates of human chromosome 2. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome vary. Among various projects, the collaborative consensus coding sequence project takes an extremely conservative strategy. So CCDS's gene number ...
Estimates of the number of coding genes in the human genome reached upwards of 100,000 prior to the human genome project, [18] but since have dwindled to as low as 19,000 following completion of that massive sequencing effort and subsequent refinements. [1]
The human genome consists of approximately 3 billion DNA base pairs and is estimated to carry around 20,000 protein coding genes. In designing the study the consortium needed to address several critical issues regarding the project metrics such as technology challenges, data quality standards and sequence coverage.