Search results
Results from the WOW.Com Content Network
The common biomolecular mechanisms underlying addiction – CREB and ΔFosB – were reviewed by Eric J. Nestler in a 2013 review. [3] Genetics and mental disorders may precipitate the severity of a drug addiction. It is estimated that 50% of healthy individuals developing an addiction can trace the cause to genetic factors. [4]
There are a range of genetic and environmental risk factors for developing an addiction that vary across the population. [ 2 ] [ 4 ] [ 5 ] Genetic and environmental risk factors each account for roughly half of an individual's risk for developing an addiction; [ 2 ] the contribution from epigenetic (inheritable traits) [ 6 ] risk factors to the ...
Current evidence indicates that in both men and women, alcoholism is 50–60% genetically determined, leaving 40-50% for environmental influences. [ 8 ] In a review in 2001, McLellan et al. compared the diagnoses, heritability, etiology (genetic and environmental factors), pathophysiology, and response to treatments (adherence and relapse) of ...
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...
Studies have proven that genetic variations and differences in our neurobiology can alter an individual's vulnerability to developing an addiction. [32] Estimates have shown that around 40%-60% of the susceptibility of an individual to develop an addiction to drugs, nicotine, and alcohol is allotted to genetic variables. [ 32 ]
Addiction is classified as a chronic brain disorder by the American Society of Addiction Medicine (ASAM). [5] There are several reasons why people develop an addiction. A predisposition to the addictive qualities of substances may be inherited by some people, making it a genetic circumstance. Another cause for addictions could be the environment.
Chemistry, not moral failing, accounts for the brain’s unwinding. In the laboratories that study drug addiction, researchers have found that the brain becomes conditioned by the repeated dopamine rush caused by heroin. “The brain is not designed to handle it,” said Dr. Ruben Baler, a scientist with the National Institute on Drug Abuse.
Another important concern is the lack of evidence supporting the addictive personality label and the possibility of stigma. [2] While there is a medical consensus surrounding the genetic components of addiction, [5] there is no such consensus supporting the idea that specific personality types have a tendency towards addictive behaviors. [2]