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  2. Glyoxylate cycle - Wikipedia

    en.wikipedia.org/wiki/Glyoxylate_cycle

    The glyoxylate cycle uses five of the eight enzymes associated with the tricarboxylic acid cycle: citrate synthase, aconitase, succinate dehydrogenase, fumarase, and malate dehydrogenase. The two cycles differ in that in the glyoxylate cycle, isocitrate is converted into glyoxylate and succinate by isocitrate lyase (ICL) instead of into α ...

  3. Glyoxylate and dicarboxylate metabolism - Wikipedia

    en.wikipedia.org/wiki/Glyoxylate_and_dicarboxyl...

    Glyoxylate and dicarboxylate metabolism describes a variety of reactions involving glyoxylate or dicarboxylates.Glyoxylate is the conjugate base of glyoxylic acid, and within a buffered environment of known pH such as the cell cytoplasm these terms can be used almost interchangeably, as the gain or loss of a hydrogen ion is all that distinguishes them, and this can occur in the aqueous ...

  4. Glyoxylate reductase - Wikipedia

    en.wikipedia.org/wiki/Glyoxylate_reductase

    Glyoxylate reductase uses NAD(P)H to reduce an oxoacid (glyoxylate) to its corresponding α-hydroxy acid (glycolate). This class of reactions provides an opportunity for the synthesis of chiral hydroxy acids. Such products are of interest in the synthesis of pharmaceuticals, such as anti-obesity compounds and semisynthetic penicillins. [13]

  5. Malate synthase - Wikipedia

    en.wikipedia.org/wiki/Malate_synthase

    In enzymology, a malate synthase (EC 2.3.3.9) is an enzyme that catalyzes the chemical reaction acetyl-CoA + H 2 O + glyoxylate → {\displaystyle \rightarrow } ( S )-malate + CoA The 3 substrates of this enzyme are acetyl-CoA , H 2 O , and glyoxylate , whereas its two products are ( S )-malate and CoA .

  6. Hopkins–Cole reaction - Wikipedia

    en.wikipedia.org/wiki/Hopkins–Cole_reaction

    The Hopkins-Cole reaction, also known as the glyoxylic acid reaction, is a chemical test used for detecting the presence of tryptophan in proteins. [1] A protein solution is mixed with Hopkins Cole reagent, which consists of glyoxylic acid. Concentrated sulfuric acid is slowly added to form two layers. A purple ring appears between the two ...

  7. Adamkiewicz reaction - Wikipedia

    en.wikipedia.org/wiki/Adamkiewicz_reaction

    The reaction relies on the interaction between glyoxylic acid and the indole ring of the amino acid tryptophan, a structural feature found in most proteins. When proteins are exposed to concentrated sulfuric acid and glyoxylic acid, the indole group undergoes a reaction that produces a highly colored compound.

  8. Glyoxylic acid - Wikipedia

    en.wikipedia.org/wiki/Glyoxylic_acid

    Glyoxylic acid is one of several ketone- and aldehyde-containing carboxylic acids that together are abundant in secondary organic aerosols. In the presence of water and sunlight, glyoxylic acid can undergo photochemical oxidation. Several different reaction pathways can ensue, leading to various other carboxylic acid and aldehyde products. [31]

  9. Alanine—glyoxylate transaminase - Wikipedia

    en.wikipedia.org/wiki/Alanine—glyoxylate...

    In enzymology, an alanine-glyoxylate transaminase (EC 2.6.1.44) is an enzyme that catalyzes the chemical reaction L-alanine + glyoxylate ⇌ {\displaystyle \rightleftharpoons } pyruvate + glycine Thus, the two substrates of this enzyme are L-alanine and glyoxylate , whereas its two products are pyruvate and glycine .