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Radiotherapy is a valid first option for MALT lymphoma. It provides local control and potential cure in localized gastric stage IE and II 1E disease with 5-year EFS of 85-100% reported in retrospective studies. [13] [14] However, the irradiation field is potentially large as it must include the whole stomach, which can vary greatly in size and ...
The mucosa-associated lymphoid tissue (MALT), also called mucosa-associated lymphatic tissue, is a diffuse system of small concentrations of lymphoid tissue found in various submucosal membrane sites of the body, such as the gastrointestinal tract, nasopharynx, thyroid, breast, lung, salivary glands, eye, and skin.
Primary gastric lymphoma (lymphoma that originates in the stomach itself) [1] is an uncommon condition, accounting for less than 15% of gastric malignancies and about 2% of all lymphomas. However, the stomach is a very common extranodal site for lymphomas (lymphomas originate elsewhere and metastasise to the stomach). [2]
Stomach cancer, also known as gastric cancer, is a malignant tumor of the stomach. It is a cancer that develops in the lining of the stomach. [10] Most cases of stomach cancers are gastric carcinomas, which can be divided into a number of subtypes, including gastric adenocarcinomas. [2] Lymphomas and mesenchymal tumors may also develop in the ...
The stomach does vary in size but its J shape is constant. [citation needed] The stomach lies in the upper part of the abdomen just below the left rib cage. The term gastropathy means "stomach disease" and is included in the name of the diseases portal hypertensive gastropathy, hyperplastic hypersecretory gastropathy (Ménétrier's disease ...
Gut-associated lymphoid tissue (GALT) [1] is a component of the mucosa-associated lymphoid tissue (MALT) which works in the immune system to protect the body from invasion in the gut. Owing to its physiological function in food absorption, the mucosal surface is thin and acts as a permeable barrier to the interior of the body.
A MALT lymphoma may rarely transform into a more aggressive diffuse large B-cell lymphoma (DLBCL). [173] Where this is associated with H. pylori infection, the DLBCL is less aggressive and more amenable to treatment. [174] [175] [176] When limited to the stomach, they have sometimes been successfully treated with H. pylori eradication programs.
Extranodal marginal zone lymphomas (EMZLs) are a form of MZL [9] in which malignant marginal zone B-cells initially infiltrate MALT tissues of the stomach (50-70% of all EMZL) or, less frequently, the esophagus, small intestine, large intestine, rectum, conjunctiva of the eye, nasal passages, pharynx, lung bronchi, vulva, vagina, skin, breast, thymus gland, meninges (i.e. membranes) that ...