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The serum half-life of ciprofloxacin is about 4–6 hours, with 50–70% of an administered dose being excreted in the urine as unmetabolized drug. An additional 10% is excreted in urine as metabolites. Urinary excretion is virtually complete 24 hours after administration. Dose adjustment is required in the elderly and in those with renal ...
Ciprofloxacin/celecoxib or PrimeC is a fixed-dose combination of ciprofloxacin and celecoxib developed for ALS. [1] [2] References
Eye, ear or bladder infections; usually applied directly to the eye or inhaled into the lungs; rarely given by injection, although the use of intravenous colistin is experiencing a resurgence due to the emergence of multi drug resistant organisms. Kidney and nerve damage (when given by injection)
Quinolone antibiotics constitute a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. [1] They are used in human and veterinary medicine to treat bacterial infections, as well as in animal husbandry, specifically poultry production.
Ciprofloxacin, a fluoroquinolone antibiotic, has shown in vitro activity against many Gram-positive and Gram-negative bacteria including Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Pseudomonas aeruginosa.
The dose for TB meningitis is dexamethasone 8 to 12 mg daily tapered off over six weeks (for those who prefer more precise dosing should refer to Thwaites et al., 2004 [34]). The dose for pericarditis is prednisolone 60 mg daily tapered off over four to eight weeks. [medical citation needed]
50 mg 20% 4 Anileridine [16] 1 ⁄ 4: 40 mg Alphaprodine: 1 ⁄ 6: 40–60 mg Tapentadol [17] 3 ⁄ 10: 32 mg 32% (fasting) Pethidine (meperidine) 1 ⁄ 3: 30 mg SC/IV/IM. 300 mg 50–60% Orally, 100% SC/IV/IM: 3–5 5–15 sec if IV, 15–25 min if orally Dipipanone [18] [19] 2 ⁄ 5: 25 mg 3.2–3.8 hours ±4 hours Benzylfentanyl: 1 ⁄ 2: AH ...
The term injection encompasses intravenous (IV), intramuscular (IM), subcutaneous (SC) and intradermal (ID) administration. [35] Parenteral administration generally acts more rapidly than topical or enteral administration, with onset of action often occurring in 15–30 seconds for IV, 10–20 minutes for IM and 15–30 minutes for SC. [36]
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