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Genomics is an interdisciplinary field of molecular biology focusing on the structure, function, evolution, mapping, and editing of genomes.A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration.
KEGG (Kyoto Encyclopedia of Genes and Genomes) is a collection of databases dealing with genomes, biological pathways, diseases, drugs, and chemical substances.KEGG is utilized for bioinformatics research and education, including data analysis in genomics, metagenomics, metabolomics and other omics studies, modeling and simulation in systems biology, and translational research in drug development.
The first genome to be sequenced was that of the virus φX174 in 1977; [4] the first genome sequence of a prokaryote (Haemophilus influenzae) was published in 1995; [5] the yeast (Saccharomyces cerevisiae) genome was the first eukaryotic genome to be sequenced in 1996. [6]
It contains approximately 3.1 billion base pairs (3.1 Gb or 3.1 x 10 9 bp). [6] This represents the size of a composite genome based on data from multiple individuals but it is a good indication of the typical amount of DNA in a haploid set of chromosomes because the Y chromosome is quite small. [7]
A genome is divided in coding and noncoding regions, and the last step of structural annotation consists in identifying these features within the genome. In fact, the primary task in genome annotation is gene prediction , which is why numerous methods have been developed for this purpose. [ 19 ]
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...
Repeated sequences (also known as repetitive elements, repeating units or repeats) are short or long patterns that occur in multiple copies throughout the genome.In many organisms, a significant fraction of the genomic DNA is repetitive, with over two-thirds of the sequence consisting of repetitive elements in humans. [1]
The term 'pangenome' was defined with its current meaning by Tettelin et al. in 2005; [2] it derives 'pan' from the Greek word παν, meaning 'whole' or 'everything', while the genome is a commonly used term to describe an organism's complete genetic material.