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Lithium's therapeutic effects are thought to be partially attributable to its interactions with several signal transduction mechanisms. [123] The cyclic AMP secondary messenger system is shown to be modulated by lithium. Lithium was found to increase the basal levels of cyclic AMP but impair receptor-coupled stimulation of cyclic AMP production ...
Lithium orotate (C 5 H 3 LiN 2 O 4) is a salt of orotic acid and lithium.It is available as the monohydrate, LiC 5 H 3 N 2 O 4 ·H 2 O. [1] In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissolves in solution to produce free lithium ions.
The soft drink 7Up was originally named "Bib-Label Lithiated Lemon-Lime Soda" when it was formulated in 1929 because it contained lithium citrate. The beverage was a patent medicine marketed as a cure for hangover. Lithium citrate was removed from 7Up in 1948 [5] after the Food and Drug Administration banned its use in soda. [6]
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The mechanism of lithium include the inhibition of GSK-3, it is a glutamate antagonism at NMDA receptors that together make lithium a neuroprotective medicine. The drug relieves bipolar symptoms, aggressiveness and irritability. Lithium has many, many side effects and requires weekly blood tests to tests for toxicity of the drug. [citation ...
Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
Lumateperone, sold under the brand name Caplyta, is an atypical antipsychotic medication of the butyrophenone class. It is approved for the treatment of schizophrenia as well as bipolar depression, as either monotherapy or adjunctive therapy (with lithium or valproate). [2]
Lithium aspartate (C 4 H 6 LiNO 4) is a salt of aspartic acid and lithium.It is sometimes marketed as a dietary supplement used in small doses to treat certain medical conditions; however, there are no systematic reviews supporting the efficacy, or safety of lithium aspartate and it is not approved by the U.S. Food and Drug Administration (FDA) for the treatment of any medical condition.