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  2. Viral pathogenesis - Wikipedia

    en.wikipedia.org/wiki/Viral_pathogenesis

    A viral infection does not always cause disease. A viral infection simply involves viral replication in the host, but disease is the damage caused by viral multiplication. [5] An individual who has a viral infection but does not display disease symptoms is known as a carrier. [17] Mechanisms by which viruses cause damage and disease to host cells

  3. Endothelial cell tropism - Wikipedia

    en.wikipedia.org/wiki/Endothelial_cell_tropism

    As endothelial cells line these blood vessels and critical networks that extend access to various human organ systems, the virus entry into these cells can be detrimental to virus spread across the host system and affect clinical course of disease. Understanding the mechanisms of how viruses attach, enter, and control endothelial functions and ...

  4. Human pathogen - Wikipedia

    en.wikipedia.org/wiki/Human_pathogen

    A human pathogen is a pathogen (microbe or microorganism such as a virus, bacterium, prion, or fungus) that causes disease in humans.. The human physiological defense against common pathogens (such as Pneumocystis) is mainly the responsibility of the immune system with help by some of the body's normal microbiota.

  5. Virus - Wikipedia

    en.wikipedia.org/wiki/Virus

    Viruses have different mechanisms by which they produce disease in an organism, which depends largely on the viral species. Mechanisms at the cellular level primarily include cell lysis, the breaking open and subsequent death of the cell. In multicellular organisms, if enough cells die, the whole organism will start to suffer the effects.

  6. Virulence factor - Wikipedia

    en.wikipedia.org/wiki/Virulence_factor

    Viruses also have notable virulence factors. Experimental research, for example, often focuses on creating environments that isolate and identify the role of "niche-specific virulence genes". These are genes that perform specific tasks within specific tissues/places at specific times; the sum total of niche-specific genes is the virus' virulence.

  7. Host–pathogen interaction - Wikipedia

    en.wikipedia.org/wiki/Host–pathogen_interaction

    Viruses, however, use a completely different mechanism to cause disease. Upon entry into the host, they can do one of two things. Many times, viral pathogens enter the lytic cycle; this is when the virus inserts its DNA or RNA into the host cell, replicates, and eventually causes the cell to lyse, releasing more viruses into the environment.

  8. Infection - Wikipedia

    en.wikipedia.org/wiki/Infection

    An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. [1] An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection.

  9. Pathogenesis - Wikipedia

    en.wikipedia.org/wiki/Pathogenesis

    In pathology, pathogenesis is the process by which a disease or disorder develops. It can include factors which contribute not only to the onset of the disease or disorder, but also to its progression and maintenance. [1] The word comes from Ancient Greek πάθος (pathos) 'suffering, disease' and γένεσις (genesis) 'creation'.