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A viral infection does not always cause disease. A viral infection simply involves viral replication in the host, but disease is the damage caused by viral multiplication. [5] An individual who has a viral infection but does not display disease symptoms is known as a carrier. [17] Mechanisms by which viruses cause damage and disease to host cells
It has been noted that a leading hypothesis for the pathogenesis of Kawasaki disease also involves a hyperinflammatory response to viral infection (such as by a novel RNA virus [47] [77]) in some genetically predisposed children, and that SARS-CoV-2 is now "added to the list" of implicated viral triggers. [48]
The term childhood disease refers to disease that is contracted or becomes symptomatic before the age of 18 or 21 years old. Many of these diseases can also be contracted by adults. Some childhood diseases include:
Antibody-dependent enhancement (ADE), sometimes less precisely called immune enhancement or disease enhancement, is a phenomenon in which binding of a virus to suboptimal antibodies enhances its entry into host cells, followed by its replication.
Rotaviruses are the most common cause of diarrhoeal disease among infants and young children. [1] Nearly every child in the world is infected with a rotavirus at least once by the age of five. [2] Immunity develops with each infection, so subsequent infections are less severe. Adults are rarely affected. [3]
Viruses, however, use a completely different mechanism to cause disease. Upon entry into the host, they can do one of two things. Many times, viral pathogens enter the lytic cycle; this is when the virus inserts its DNA or RNA into the host cell, replicates, and eventually causes the cell to lyse, releasing more viruses into the environment.
Some viral infections can also be latent, examples of latent viral infections are any of those from the Herpesviridae family. [55] The word infection can denote any presence of a particular pathogen at all (no matter how little) but also is often used in a sense implying a clinically apparent infection (in other words, a case of infectious ...
The virus utilizes host proteins and other cell machinery to replicate. Once the viral genome has been replicated, the progeny virions are assembled and released out of the cell. Viral pathogens capitalize on cell surface receptors that are ubiquitous and can recognize many diverse ligands for attachment and ultimately, entry into the cell.