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[citation needed] Its duration of action is 4 hours with intramuscular injection and 30 minutes with intravenous administration. [citation needed] Mephentermine, along with phentermine, is known to be produced as a metabolite of the orally administered local anesthetic oxetacaine (oxethazaine). [12] [13]
Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant effects. [8] [9] [10] Chemically, it is a substituted amphetamine. [11] Phentermine was approved for medical use in the United States in 1959. [3] It is available as a generic medication. [3]
Phentermine and topiramate was developed by Vivus, a California pharmaceutical company. In December 2009, Vivus, Inc. submitted a new drug application (NDA) to the FDA and on 1 March 2010, Vivus, Inc. announced that the FDA accepted the NDA for review.
One 2024 study found that 15.8 million Americans now live in pharmacy deserts, and that those communities have a high proportion of people with a high-school education or less and who have no ...
Canada, UK, US Carcinogen. [22] Etretinate: 1989 France Teratogen. [2] [3] Exifone: 1989 France Hepatotoxicity. [3] Fen-phen (popular combination of fenfluramine and phentermine) 1997 Cardiotoxicity Fenclofenac: 1984 UK Cutaneous reactions; animal carcinogenicity. [3] Fenclozic acid: 1970 UK, US Hepatotoxicity. [3] Fenfluramine: 1997
Chlorphentermine, sold under the brand names Apsedon, Desopimon, and Lucofen, is a serotonergic appetite suppressant of the amphetamine family. Developed in 1962, it is the para-chloro derivative of the better-known appetite suppressant phentermine, which is still in current use.
A few facts for you according to the folks from The Anxiety and Depression Association of America and the National Institute of Mental Health: In 2020, an estimated 14.8 million U.S. adults aged ...
Substituted amphetamines, or simply amphetamines, are a class of compounds based upon the amphetamine structure; [1] it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents.
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