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Eurycoma longifolia (commonly called tongkat ali, Malaysian ginseng or long jack) [3] is a flowering plant in the family Simaroubaceae. It is native to Indochina (Cambodia, Laos, Malaysia, Myanmar, Thailand and Vietnam) and Indonesia (the islands of Borneo and Sumatra ), [ 4 ] but has also been found in the Philippines. [ 5 ]
Eurycomanone is a chemical compound that has been isolated from Eurycoma longifolia, also known as the longjack plant or tongkat ali. [1] Eurycomanone is distributed throughout the plant, with the highest concentration in leaves. Researchers measured 6.0568 μg/mL in leaves, and only 0.3533 μg/mL in roots. [2]
A follow-up period of at least 10-15 years would be ideal to better evaluate long-term associations between antibiotic use and cognitive decline, as dementia and cognitive impairments often ...
Antihistamines are usually for short-term treatment. [1] Chronic allergies increase the risk of health problems which antihistamines might not treat, including asthma, sinusitis, and lower respiratory tract infection. [1] Consultation of a medical professional is recommended for those who intend to take antihistamines for longer-term use. [1]
Tongkat Ali, a south-east Asian medicinal plant (also called Eurycoma longifolia Jack or Malaysian ginseng), is one of the most commonly touted testosterone-boosting herbs.
As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
The term "anticholinergic" is typically used to refer to antimuscarinics that competitively inhibit the binding of ACh to muscarinic acetylcholine receptors; such agents do not antagonize the binding at nicotinic acetylcholine receptors at the neuromuscular junction, although the term is sometimes used to refer to agents that do so. [3] [5]
Chlorphenamine produces less sedation than other first-generation antihistamines. [10] A large study on people 65 years old or older linked the development of Alzheimer's disease and other forms of dementia to the "higher cumulative" use of chlorphenamine and other first-generation antihistamines, due to their anticholinergic properties. [11]