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[3] [4] Systemic manifestations occur at the time of skin manifestations and include a high number of eosinophils in the blood, liver inflammation, and interstitial nephritis. However, a subgroup of patients may become hypothyroid as part of an autoimmune thyroiditis up to 2 months after the initiation of symptoms.
Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [2] used for the treatment of major depressive disorder, anxiety, obsessive–compulsive disorder (OCD), panic disorder, premenstrual dysphoric disorder, and bulimia nervosa. [2]
Cosmetic psychopharmacology, a term coined in 1990 by the psychiatrist Peter D. Kramer and popularized in his 1993 book Listening to Prozac, refers to the use of drugs to move persons from a normal psychological state to another normal state that is more desired or better socially rewarded — e.g., from melancholy towards assertiveness and confidence or from slower to quicker cognition.
Fluoxetine (Prozac) Paroxetine (Paxil, Pexeva) ... tingling sensation on the skin) Irritability. Headache. ... If you have a history of heart problems — such as QT prolongation and heart rhythm ...
[181] [182] Discontinuation effects appear to be less for fluoxetine, perhaps owing to its long half-life and the natural tapering effect associated with its slow clearance from the body. One strategy for minimizing SSRI discontinuation symptoms is to switch the patient to fluoxetine and then taper and discontinue the fluoxetine. [181]
Fluoxetine, however, has produced positive results in the treatment of pathological skin picking disorder, [4] [15] although more research is needed to conclude this information. Fluoxetine has also been evaluated in treating IED and demonstrated significant improvement in reducing frequency and severity of impulsive aggression and irritability ...
During the five years of research, up to 15 generations of the guppies were exposed to three different levels of fluoxetine at 0, 31.5 and 316 nanograms per liter (ng/L) while researchers observed ...
The problem has been poorly studied, and most of the literature has been case reports or small clinical studies; incidence is hard to determine and controversial. [21] With the explosion of use and interest in SSRIs in the late 1980s and early 1990s, focused especially on Prozac, interest grew as well in discontinuation syndromes. [30]
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