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Isopropyl alcohol (IUPAC name propan-2-ol and also called isopropanol or 2-propanol) is a colorless, flammable, organic compound with a pungent alcoholic odor. [9]Isopropyl alcohol, an organic polar molecule, is miscible in water, ethanol, and chloroform, demonstrating its ability to dissolve a wide range of substances including ethyl cellulose, polyvinyl butyral, oils, alkaloids, and natural ...
Side effects of alcohols applied to the skin include skin irritation. [2] Care should be taken with electrocautery, as ethanol is flammable. [1] Types of alcohol used include ethanol, denatured ethanol, 1-propanol, and isopropyl alcohol. [6] [7] Alcohols are effective against a range of microorganisms, though they do not inactivate spores. [7]
Isopropyl rubbing alcohols contain from 50% to 99% by volume of isopropyl alcohol, the remainder consisting of water. Boiling points vary with the proportion of isopropyl alcohol from 80 to 83 °C (176 to 181 °F); likewise, freezing points vary from −32 to −50 °C (−26 to −58 °F). [6] Surgical spirit BP boils at 80 °C (176 °F). [7]
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Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. It is also used as a treatment for head lice . [ 2 ] It is also in flea and tick killing products for pets.
Isopropyl alcohol will kill 99.99% or more of all non-spore forming bacteria in less than 30 seconds, both in the laboratory and on human skin. [ 26 ] [ 31 ] In too low quantities (0.3 ml) or concentrations (below 60%), the alcohol in hand sanitizers may not have the 10–15 seconds exposure time required to denature proteins and lyse cells. [ 4 ]
Skin disinfection may be accomplished with a number of solutions including providone-iodine, chlorhexidine, alcohol based solutions, and cetrimide. [2] There is strong evidence that chlorhexidine and denatured alcohol use to clean skin prior to surgery is better than any other commercially available antiseptic, such as povidone-iodine with alcohol.
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