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Detoxification or detoxication (detox for short) [1] is the physiological or medicinal removal of toxic substances from a living organism, including the human body, ...
[10] [11] [12] Notions of internal cleansing had resurgence along with the rise of alternative medicine in the 1970s and following; it remains unscientific and anachronistic. [10] With the rise of the environmentalist movement, many detox diets use the diet format as a political platform to advocate for environmental ideas about pollution and ...
Some addiction medicine practitioners use the term withdrawal management instead of detoxification. [ 1 ] [ 2 ] A detoxification program for physical dependence does not necessarily address the precedents of addiction , social factors, psychological addiction, or the often-complex behavioral issues that intermingle with addiction.
Cytochrome P450 oxidases are important enzymes in xenobiotic metabolism.. Xenobiotic metabolism (from the Greek xenos "stranger" and biotic "related to living beings") is the set of metabolic pathways that modify the chemical structure of xenobiotics, which are compounds foreign to an organism's normal biochemistry, such as drugs and poisons.
[1] [2] This system has been studied in both bacteria and eukaryotes. [ 2 ] [ 3 ] [ 4 ] This detoxification is accomplished by the sequential action of two thiol-dependent enzymes; firstly glyoxalase І , which catalyzes the isomerization of the spontaneously formed hemithioacetal adduct between glutathione and 2-oxoaldehydes (such as ...
Alcohol detoxification (also known as detox) is the abrupt cessation of alcohol intake in individuals that have alcohol use disorder. This process is often coupled with substitution of drugs that have effects similar to the effects of alcohol in order to lessen the symptoms of alcohol withdrawal .
Alcohol detoxification, medical treatment for alcohol dependence through the abrupt cessation; Drug detoxification, any of various treatments for drug abuse or overdose; Heavy metal detoxification, removal of toxic heavy metals from the body Chelation therapy, a form of heavy metal detoxification involving the administration of chelating agents
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]