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The hippocampus (pl.: hippocampi; via Latin from Greek ἱππόκαμπος, 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus, and the subiculum are components of the hippocampal formation located in the limbic system.
The hippocampus is a five centimetre long ridge of gray matter tissue within the parahippocampal gyrus that can only be seen when the gyrus is opened up. [1] [2] The hippocampus is described in three regions, a head, body, and tail. The head is the expanded part near to the temporal lobe.
The hippocampus, or hippocamp or hippokampos (plural: hippocampi or hippocamps; Ancient Greek: ἱππόκαμπος, from ἵππος, 'horse', and κάμπος, 'sea monster' [1]), sometimes called a "sea-horse" [2] in English, [citation needed] is a mythological creature mentioned in Etruscan, Greek, Phoenician, [3] Pictish and Roman ...
Typically, the hippocampal formation is said to included the dentate gyrus, the hippocampus, and the subiculum. [2] The presubiculum, parasubiculum, and the entorhinal cortex may also be included. [3] The hippocampal formation is thought to play a role in memory, spatial navigation and control of attention.
CA3a is the part of the cell band that is most distant from the dentate (and closest to CA1). CA3b is the middle part of the band nearest to the fimbria and fornix connection. CA3c is nearest to the dentate, inserting into the hilus. CA3 overall, has been considered to be the “pacemaker” of the hippocampus.
The fornix is the conduit by which the neurotransmitter acetylcholine – which is crucial for memory encoding – is sent from the medial septum/Diagonal band of Broca to the hippocampus. [7] In addition, the GABA-producing neurons in the septal nuclei generate theta rhythms which are transmitted through the fornix to the hippocampus.
The cerebrum (pl.: cerebra), telencephalon or endbrain [1] is the largest part of the brain, containing the cerebral cortex (of the two cerebral hemispheres) as well as several subcortical structures, including the hippocampus, basal ganglia, and olfactory bulb. In the human brain, the cerebrum is the uppermost region of the central nervous system.
The dentate gyrus (DG) is one of the subfields of the hippocampus, in the hippocampal formation.The hippocampal formation is located in the temporal lobe of the brain, and includes the hippocampus (including CA1 to CA4) subfields, and other subfields including the dentate gyrus, subiculum, and presubiculum.