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Reelin's name comes from the abnormal reeling gait of reeler mice, [17] which were later found to have a deficiency of this brain protein and were homozygous for mutation of the RELN gene. The primary phenotype associated with loss of reelin function is a failure of neuronal positioning throughout the developing central nervous system (CNS).
The Disabled-1 (Dab1) gene encodes a key regulator of Reelin signaling. Reelin is a large glycoprotein secreted by neurons of the developing brain, particularly Cajal-Retzius cells. DAB1 functions downstream of Reln in a signaling pathway that controls cell positioning in the developing brain and during adult neurogenesis.
Microsoft Office Excel – for MS Windows and Apple Macintosh. The proprietary spreadsheet leader. Microsoft Works Spreadsheet – for MS Windows (previously MS-DOS and Apple Macintosh). Only allows one sheet at a time. PlanMaker – for MS Windows, Linux, MS Windows Mobile and CE; part of SoftMaker Office
The template is intended for conversion of heights specified in either metres or in feet and inches. Template parameters [Edit template data] Parameter Description Type Status Metres m metre metres meter meters The height in metres. Do not use if feet and inches are specified. Number optional Centimetres cm centimetre centimetres centimeter centimeters The height in centimetres. Do not use if ...
In size theory, the size function (,): + = {(,): <} associated with the size pair (,:) is defined in the following way. For every (,) +, (,) (,) is equal to the number of connected components of the set {: ()} that contain at least one point at which the measuring function (a continuous function from a topological space to [1] [2]) takes a value smaller than or equal to . [3]
Rack with sample component sizes including an A/V half-rack unit. A rack unit (abbreviated U or RU) is a unit of measure defined as 1 + 3 ⁄ 4 inches (44.45 mm). [1] [2] It is most frequently used as a measurement of the overall height of 19-inch and 23-inch rack frames, as well as the height of equipment that mounts in these frames, whereby the height of the frame or equipment is expressed ...
A reference dimension is a dimension on an engineering drawing provided for information only. [1] Reference dimensions are provided for a variety of reasons and are often an accumulation of other dimensions that are defined elsewhere [2] (e.g. on the drawing or other related documentation). These dimensions may also be used for convenience to ...
In genetics, rs7341475 is a single nucleotide polymorphism (SNP) in the RELN gene that codes the reelin protein. The gene RELN is mapped to human chromosome 7 (7q22.1). The SNP rs7341475 is located in the fourth intron of RELN. The gene RELN has many more SNPs among its 65 exons and 64 introns, — even in intron 4 there are tens of SNPs. [1]