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Its use during pregnancy is contraindicated, although it has been placed in Australian pregnancy category C. [13] Its use during the first trimester (during organogenesis) and 12 weeks prior to pregnancy has been associated with an increased risk of congenital malformations, especially malformations associated with maternal folic acid ...
Clarithromycin can be taken by mouth as a tablet or liquid or can be infused intravenously. [3] Common side effects include nausea, vomiting, headaches, and diarrhea. [3] Severe allergic reactions are rare. [3] Liver problems have been reported. [3] It may cause harm if taken during pregnancy. [3]
Based on the studies that show that trimethoprim crosses the placenta and can affect folate metabolism, there has been growing evidence of the risk of structural birth defects associated with trimethoprim, especially during the first trimester of pregnancy. [21] The trophoblasts in the early fetus are sensitive to changes in the folate cycle.
Usage of aspirin for pain relief during pregnancy is not recommended. Aspirin use during pregnancy has not demonstrated an increased risk of spontaneous abortion within the early weeks of pregnancy. However, its usage during organogenesis and the third trimester can lead to elevated risk of intrauterine growth retardation and maternal ...
Hypertensive disorders during pregnancy, such as gestational hypertension, preeclampsia, and eclampsia, are a major contributor to maternal and fetal illness and death on a worldwide scale. Around 5-10% of pregnancies are affected by these conditions, with preeclampsia being responsible for up to 14% of maternal deaths globally.
The heart adapts to the increased cardiac demand that occurs during pregnancy in many ways. Cardiac output (Lit./Min.): 6.26; Stroke Volume (Ml.): 75; Heart Rate (Per min.): 85; Blood Pressure: Unaffected; Cardiac output increases throughout early pregnancy, and peaks in the third trimester, usually to 30-50% above baseline. [6]
Anemia prevalences during pregnancy differed from 18% in developed countries to 75% in South Asia; culminating to a global rate of 38% of pregnancies worldwide. [ 1 ] [ 5 ] [ 32 ] Treatment varies due to the severity of the anaemia, and can be used by increasing iron containing foods, oral iron tablets or by the use of parenteral iron .
Severe and disseminated coccidioidomycosis has been reported to occur in increased frequency in pregnant women in several reports and case series, but subsequent large surveys, with the overall risk being rather low. [1] Varicella occurs at an increased rate during pregnancy, but mortality is not higher than that among men and non-pregnant ...