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Until 2006, NyQuil Cold/Flu Multisymptom Relief and NyQuil Sinus contained pseudoephedrine (30 mg/15 mL), a nasal decongestant that also formed the active ingredient in Sudafed. Following the passage of the Combat Methamphetamine Epidemic Act in 2006, in the United States all pseudoephedrine-containing medications must be kept behind a pharmacy ...
Although this bill extended to the drugs ephedrine and pseudoephedrine, it was used as a starting point for building the bill for dextromethorphan. This bill provided that any infraction of a provider in an over-the-counter sale who willfully and knowingly supply, deliver, or give possession of a non-prescription drug that contains ...
Those original versions of Sudafed and other medicines remain available without a prescription, but they're less popular and account for about one-fifth of the $2.2 billion market for oral ...
In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg. Doses as high as 15–20 mg/kg are taken by some recreational users. A single case study suggests that the antidote to dextromethorphan overdose is naloxone, administered intravenously. [17]
Heated cough syrup can also vaporize, leading to inhalation hazards. [46] [47] [48] The warning received attention from many news outlets, but some criticized the FDA's handling of the issue for amplifying the attention the topic received online and questioned if making and eating NyQuil chicken actually existed as a widespread trend. [49] [50 ...
NyQuil used to contain the nasal decongestant pseudoephedrine. Some pharmacies stock medications with pseudoephedrine behind the counter due to fears that they will be used as an ingredient to produce illegal drugs. Because taking the product off store shelves negatively impacts sales, the pseudoephedrine was removed from the formula.
Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder.
Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. [1] [13] [2] It has also been used off-label for certain other indications, like treatment of low blood pressure.
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