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Prostate cancer antigen 3 is a urine test that detects the overexpression of the PCA3 gene, an indicator of prostate cancer. [32] [46] [47] [44] ConfirmMDx is performed on tissue taken during a prostate biopsy. The test identifies men with clinically significant prostate cancer who would benefit from further testing and treatment.
Prostate biopsy is a procedure in which small hollow needle-core samples are removed from a man's prostate gland to be examined for the presence of prostate cancer. It is typically performed when the result from a PSA blood test is high. [1] It may also be considered advisable after a digital rectal exam (DRE) finds possible abnormality.
Digital rectal examination (DRE), also known as a prostate exam (Latin: palpatio per anum (PPA), lit. 'palpation through the anus'), is an internal examination of the rectum performed by a healthcare provider .
Men suspected of having prostate cancer may undergo several tests to assess the prostate. One common procedure is the digital rectal examination, in which a doctor inserts a lubricated finger into the rectum to feel the nearby prostate. [23] [24] Tumors feel like stiff, irregularly shaped lumps against the rest of the prostate.
In this procedure, a doctor inserts an ultrasound probe into the rectum, enabling them to see the prostate gland. Next, they insert a long, narrow tube called a cystoscope into the bladder.
Transrectal ultrasonography, or TRUS in short, is a method of creating an image of organs in the pelvis, most commonly used to perform an ultrasound-guided needle biopsy evaluation of the prostate gland in men with elevated prostate-specific antigen or prostatic nodules on digital rectal exam.
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