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5-Methyltryptamine (5-MeT, 5-Me-T) is a non-selective serotonin receptor agonist and serotonin releasing agent of the tryptamine family that has been used in scientific research. [ 1 ] [ 2 ] It is related to other 5- substituted tryptamines such as serotonin (5-hydroxytryptamine; 5-HT) and 5-methoxytryptamine (5-MeO-T).
5-Methoxytryptamine (5-MT, 5-MeO-T, or 5-OMe-T), also known as serotonin methyl ether or O-methylserotonin and as mexamine, is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin. [3] It has been shown to occur naturally in the body in low levels, especially in the pineal gland.
5-Methoxy-7,N,N-trimethyltryptamine (5-MeO-7,N,N-TMT, 5-MeO-7-TMT), is a tryptamine derivative which acts as a partial agonist at the 5-HT 2 serotonin receptors, with an EC 50 of 63.9 nM and an efficacy of 66.2% at 5-HT 2A (vs 5-HT), and weaker activity at 5-HT 2B and 5-HT 2C. [1] [2] [3] In animal tests, both 7,N,N-TMT and 5-MeO-7,N,N-TMT ...
5-Methoxy-N-propyl-N-isopropyltryptamine (5-MeO-PiPT) is a substituted tryptamine derivative which is claimed to have psychedelic effects. It acts as a 5-HT 1A and 5-HT 2A receptor agonist, [ 1 ] with an EC 50 of 13.8 nM and an efficacy of 89% (vs 5-HT), [ 2 ] and has been sold as a designer drug , first being identified in 2021 in British ...
5-Methoxy-2,N,N-trimethyltryptamine (5-MeO-2,N,N-TMT, 5-MeO-TMT) is a psychoactive drug of the tryptamine chemical class which acts as a psychedelic.It was first synthesized by Alexander Shulgin and reported in his book TiHKAL ("Tryptamines i Have Known And Loved").
5-MeO-NBpBrT (5-Methoxy-N-(4-bromobenzyl)tryptamine) is a N-substituted member of the methoxytryptamine family of compounds. Like other such compounds it acts as an antagonist for the 5-HT 2A receptor , with a claimed 100x selectivity over the closely related 5-HT 2C receptor. [ 1 ]
Little is known about the subjective effects of 5-MeO-DPT, but the nature of the compound is probably comparable to 5-MeO-DiPT, 5-MeO-DMT, or DPT, which are also psychedelic tryptamines/indoles. However, the duration of the above-mentioned drugs vary considerably.
α-Methylmelatonin, also known as α-methyl-5-methoxy-N-acetyltryptamine, is a synthetic tryptamine derivative and analogue of the monoamine neurotransmitter melatonin. [1] It is a metabolite of α-methyltryptophan , α-methyl-5-hydroxytryptophan , and α-methylserotonin that can be formed in small amounts via aralkylamine N -acetyltransferase ...