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Topical tretinoin is for use only on the skin and should not be applied to eyes or mucosal tissues. Common side effects include skin irritation, redness, swelling, and blistering. [ 6 ] If irritation is a problem, a decrease in the frequency of application to every other or every third night can be considered, and the frequency of application ...
retinol, retinal, tretinoin (retinoic acid), isotretinoin, and alitretinoin: Second generation: Synthetic analogs formulated for oral dosing. There are no topically available second generation formulations of retinoids. etretinate and its metabolite acitretin: Third generation: Retinoidal benzoic acid derivatives: adapalene, bexarotene, and ...
Zein E. Obagi is a Syrian-American [1] dermatologist who is the founder and medical director of ZO Skin Health, Inc. based in Beverly Hills, California. He is also the head of the Obagi Skin Health Institute. He is credited with popularizing the idea of "skin health for the mass market" in the 1980s. [2]
Tretinoin/benzoyl peroxide, sold under the brand name Twyneo, is a fixed-dose combination medication used for the treatment of acne. [1] [2] It contains tretinoin, a vitamin A derivative, and benzoyl peroxide, an oxidizing agent. [3] The combination was approved for medical use in the United States in July 2021. [2] [4] [5]
A systematic review examined the benefits and clinical efficacy of routine skin care activities, such as washing, bathing, and applying lotions, in acute and long-term care adult settings. The study led to a proposed 2-step program targeting adults with intact or preclinically damaged skin. [13]
The identification of the use of tretinoin along Dr. James E. Fulton and Dr. Gerd Plewig as a treatment for acne and wrinkles was perhaps their best-known contribution to dermatology. Sold as Retin-A, this innovation earned Kligman significant royalties. He was a generous supporter of the department of dermatology at the University of ...
Clindamycin/tretinoin is a topical gel used in the treatment of acne. The two active ingredients are the antibiotic clindamycin phosphate (1.2%) and tretinoin (0.025%), a retinoid . [ 1 ] The two active ingredients perform different functions, the clindamycin is active against gram-positive bacteria, including streptococci and penicillin ...
Tretinoin (retinoic acid)causes dispersion of pigment granules in keratinocytes,interferes with pigment transfer,and acceler-ates epidermal transfer,thus causing pigment to be lost more rapidly.Tretinoin also accelerates epidermal turnover,shorten-ing the "transit time"from the basal layer and accelerating pig-ment loss.Retinoic acid reduces ...
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