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Measured in seconds to clot formation, normal PTT can vary based on the laboratory or institution; however, normal PTT is between 25 to 35. PTT ranges are used to classify heparin dosing schemes as low or high intensity and to ensure effective dosing.
With the PTT test, the reference range is between 25 and 33 seconds. As with the PT test, a higher PTT number means your blood is taking longer than usual to clot. A lower PTT number means that your blood is clotting faster than normal.
A clotting time between 25 and 35 seconds is in the partial thromboplastin time normal range. This normal range may vary a bit from lab to lab. What does it mean when your PTT is high?
Normal PTT values range from 25 to 35 seconds. Prolonged PTT may signify deficiencies in these clotting factors, hemophilia, or the presence of inhibitors. Shortened PTT, on the other hand, may indicate an increased risk of thrombosis and could be associated with elevated factor VIII levels.
A typical value for a PTT is 60 to 70 seconds. There’s also an activated PTT (aPTT) test that measures the same thing, but they add a substance to your blood to make it clot faster.
Clinically, a PTT value exceeding the upper limit of the normal range (over 35 seconds) is considered elevated. The degree of elevation can provide clues regarding the severity and potential cause of the coagulation abnormality.
Therapeutic Range = 45 – 75 seconds (1.5 – 2.5 x MEAN NORMAL) Recently, another method of determining the Heparin Therapeutic Range was developed utilizing a procedure derived from Brill-Edwards, et al, in which aPTT values and heparin levels are obtained from patients actually receiving heparin.
If you’re getting the test to monitor heparin, your “normal” will be higher -- usually between 60 and 100 seconds. If your results are above the normal range, your blood clots more slowly. Doctors call this “prolonged” PTT.
While a normal PTT typically falls between 25 to 35 seconds, the therapeutic range for patients on heparin (a common anticoagulant) is often targeted at 1.5 to 2.5 times the normal value. But here’s where it gets interesting – the therapeutic range isn’t set in stone.
Normal Range for PTT: The normal range for PTT typically falls between 25 to 35 seconds. However, the specific reference range may vary between laboratories. Deviations from the normal range may indicate an increased risk of bleeding or thrombosis, depending on whether PTT is prolonged or shortened.