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[1] [2] [9] BP-II is more common than BP-I, while BP-II and major depressive disorder have about the same rate of diagnosis. [11] Substance use disorders (which have high co-morbidity with BP-II) and periods of mixed depression may also make it more difficult to accurately identify BP-II. [ 2 ]
A recent large-scale study found that severe depression in patients with bipolar disorder responds no better to a combination of antidepressant medications and mood stabilizers than it does to mood stabilizers alone and that antidepressant use does not hasten the emergence of manic symptoms in patients with bipolar disorder. [40]
There may also be a risk of accelerating cycling between phases when antidepressants are used in bipolar disorder. The risk of affective switches is higher in bipolar I depression; antidepressants are generally avoided in bipolar I disorder or only used with mood stabilizers when they are deemed necessary. [156] [24]: 63
Bipolar disorder is a long-term mood disorder characterized by major fluctuations in mood — both high and low — that can impact daily functioning and behavior. Bipolar Disorder: 4 Types & What ...
Omega-3 fatty acids It is also conjectured that omega-3 fatty acids may have a mood stabilizing effect. [16] Compared with placebo, omega-3 fatty acids appear better able to augment known mood stabilizers in reducing depressive (but perhaps not manic) symptoms of bipolar disorder; additional trials would be needed to establish the effects of omega-3 fatty acids alone.
Bipolar disorder is a mental disorder with cyclical periods of depression and periods of elevated mood. [1] The elevated mood is significant and is known as mania , a severe elevation that can be accompanied by psychosis in some cases, or hypomania , a milder form of mania.
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