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  2. Sertraline - Wikipedia

    en.wikipedia.org/wiki/Sertraline

    Following a single oral dose of sertraline, mean peak blood levels of sertraline occur between 4.5 and 8.4 hours. [5] Bioavailability is likely linear and dose-proportional over a dose range of 150 to 200 mg. [ 5 ] Concomitant intake of sertraline with food slightly increases sertraline peak levels and total exposure. [ 5 ]

  3. Selective serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Selective_serotonin...

    The full mechanism of action for the anti-inflammatory effects of SSRIs is not fully known. However, there is evidence for various pathways to have a hand in the mechanism. One such possible mechanism is the increased levels of cyclic adenosine monophosphate (cAMP) as a result of interference with activation of protein kinase A (PKA), a cAMP ...

  4. List of antidepressants - Wikipedia

    en.wikipedia.org/wiki/List_of_antidepressants

    This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.

  5. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

    www.aol.com/switching-antidepressants-safety...

    Common SSRIs include Prozac (fluoxetine), Zoloft (sertraline) and Lexapro (escitalopram). Effectiveness and side effect rates can vary between SSRIs. Effectiveness and side effect rates can vary ...

  6. Antidepressant - Wikipedia

    en.wikipedia.org/wiki/Antidepressant

    The effect size (SMD) for improvement with placebo in trials of antidepressants for anxiety disorders is approximately 1.0, which is a large improvement in terms of effect size definitions. [45] In relation to this, most of the benefit of antidepressants for anxiety disorders is attributable to placebo responses rather than to the effects of ...

  7. Sertraline for Depression & Anxiety: What Are the Possible ...

    www.aol.com/sertraline-depression-anxiety...

    This side effect, like others, may often be managed by reducing your dosage of sertraline or switching to a different antidepressant, such as escitalopram (Lexapro) or fluoxetine (Prozac), which ...

  8. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    This change appears to remove the antihistaminic properties of the drug. By removing the (R)-enantiomer, the lowest dose of escitalopram becomes more efficacious and faster onset than comparable dose of citalopram, where escitalopram has twice the activity of citalopram and is at least 27 times more potent than the (R)-enantiomer. [6]

  9. Dogs don't actually age 7 times faster than humans, new study ...

    www.aol.com/lifestyle/dogs-dont-actually-age-7...

    Say you have a 4-year-old Labrador named Comet — with the new equation, Comet's real "dog age" would be slightly older than 53. The reason for the difference is actually pretty simple.

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