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IgG4-related disease (IgG4-RD), formerly known as IgG4-related systemic disease, is a chronic inflammatory condition characterized by tissue infiltration with lymphocytes and IgG4-secreting plasma cells, various degrees of fibrosis (scarring) and a usually prompt response to oral steroids.
IgG4-related ophthalmic disease (IgG4-ROD) is the recommended term to describe orbital (eye socket) manifestations of the systemic condition IgG4-related disease, [2] which is characterised by infiltration of lymphocytes and plasma cells and subsequent fibrosis in involved structures. It can involve one or more of the orbital structures.
Although a clear understanding of the various skin lesions in IgG4-related disease is a work in progress, skin lesions have been classified into subtypes based on documented cases: [2] Angiolymphoid hyperplasia with eosinophilia (or lesions that mimic it) [3] and cutaneous pseudolymphoma; Cutaneous plasmacytosis [Note 1]
Michael Garron Hospital (MGH), formerly Toronto East General Hospital (TEGH), is a community teaching hospital located at 825 Coxwell Avenue in East York, Toronto, Ontario, Canada. Overview [ edit ]
The hospital now stands as the largest cancer centre in Canada [1] and one of the five largest cancer centres in the world. [2] Along with the Odette Cancer Centre , which is also associated with University of Toronto Faculty of Medicine and is independently the sixth largest cancer centre in North America, it forms one of the largest cluster ...
The program provides critical care and trauma care to patients. The emergency department is open 24 hours a day. The trauma centre is the largest in Canada, and the only accredited Level 1 trauma centre outside of the US. It is one of two trauma centres in Toronto, the other being St. Michael's Hospital. [29]
The water-accessible surface area of an IgG antibody. Immunoglobulin G (IgG) is a type of antibody.Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. [1]
The internationally recognised name for this disease has been IgG4-related disease (IgG4-RD) ... IgG4-related disease. Marcocapelle 22:26, 28 May 2015 (UTC) ...