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[1] [2] One unit of whole blood (approximately 450 mL) increases hemoglobin levels by about 10 g/L. [3] [4] Cross matching is typically done before the blood is given.
In adults, one unit brings up hemoglobin levels by about 10 g/L (1 g/dL). [3] [4] Repeated transfusions may be required in people receiving cancer chemotherapy or who have haemoglobin disorders. Cross-matching may be required before the blood is given. [1] A red blood cell concentrate is given by injection into a vein. [5]
Phlebotomies that are carried out in the treatment of some blood disorders are known as therapeutic phlebotomies. [3] The average volume of whole blood drawn in a therapeutic phlebotomy to an adult is 1 unit (450–500 ml) weekly to once every several months, as needed. [4]
Replacing breakable glass bottles with durable plastic bags made from PVC allowed for the evolution of a collection system capable of safe and easy preparation of multiple blood components from a single unit of whole blood. In the field of cancer surgery, the replacement of massive blood-loss became a major problem. The cardiac-arrest rate was ...
Single unit transfusion also applies to transfusion of fresh frozen plasma in that there should be a clinical indication for the number transfused. Coagulation studies and point of care whole blood functional assays such as TEG or ROTEM can be used to assess whether further units are required. [6] [7]
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Fresh frozen plasma (FFP) is a blood product made from the liquid portion of whole blood. [3] It is used to treat conditions in which there are low blood clotting factors (INR > 1.5) or low levels of other blood proteins. [3] [1] It may also be used as the replacement fluid in plasma exchange.
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