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Buruli ulcer is treated through a combination of antibiotics to kill the bacteria, and wound care or surgery to support the healing of the ulcer. The most widely used antibiotic regimen is once daily oral rifampicin plus twice-daily oral clarithromycin , recommended by the World Health Organization.
The Global Buruli Ulcer Initiative (GBUI) is a World Health Organization (WHO) initiative to coordinate global efforts to control Buruli ulcer, [1] an infectious disease characterized by the development of painless open wounds. [2]
The bacteria can infect humans and some other animals, causing persistent open wounds called Buruli ulcer. M. ulcerans is closely related to Mycobacterium marinum , from which it evolved around one million years ago, and more distantly to the mycobacteria which cause tuberculosis and leprosy .
This grows larger over days to weeks, forming an open ulcer (biopsy images pictured). Deep ulcers can cause scarring of muscles and tendons, resulting in permanent disability. The World Health Organization (WHO) recommends treating Buruli ulcer with a combination of the antibiotics rifampicin and clarithromycin. Regular cleaning and dressing of ...
Deep ulcers can cause scarring of muscles and tendons, resulting in permanent disability. Buruli ulcer is caused by skin infection with bacteria called Mycobacterium ulcerans . The mechanism by which M. ulcerans is transmitted from the environment to humans is not known, but may involve the bite of an aquatic insect or the infection of open wounds.
Scabies (also sometimes known as the seven-year itch) is a contagious human skin infestation by the tiny (0.2–0.45 mm) mite Sarcoptes scabiei, variety hominis. The word is from Latin: scabere, lit. 'to scratch'. The most common symptoms are severe itchiness and a pimple -like rash. Occasionally, tiny burrows may appear on the skin. In a first-ever infection, the infected person usually ...
Mycolactone is a polyketide-derived macrolide produced and secreted by a group of very closely related pathogenic mycobacteria species including M. ulcerans, M. liflandii (an unofficial designation), M. pseudoshottsii, and some strains of M. marinum.
This grows larger over days to weeks, forming an open ulcer (biopsy images pictured). Deep ulcers can cause scarring of muscles and tendons, resulting in permanent disability. The World Health Organization (WHO) recommends treating Buruli ulcer with a combination of the antibiotics rifampicin and clarithromycin. Regular cleaning and dressing of ...