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2. Transfer RNA - Wikipedia

   en.wikipedia.org/wiki/Transfer_RNA

   In the A/T site, the A-site half resides in the small ribosomal subunit where the mRNA decoding site is located. The mRNA decoding site is where the mRNA codon is read out during translation. The T-site half resides mainly on the large ribosomal subunit where EF-Tu or eEF-1 interacts with the ribosome.

3. Aminoacyl-tRNA - Wikipedia

   en.wikipedia.org/wiki/Aminoacyl-tRNA

   Research into the stability of aa-tRNAs illustrates that the acyl (or ester) linkage is the most important conferring factor, as opposed to the sequence of the tRNA itself. This linkage is an ester bond that chemically binds the carboxyl group of an amino acid to the terminal 3'-OH group of its cognate tRNA. [ 7 ]

4. Gene - Wikipedia

   en.wikipedia.org/wiki/Gene

   The primary function of the genome is to produce RNA molecules. Selected portions of the DNA nucleotide sequence are copied into a corresponding RNA nucleotide sequence, which either encodes a protein (if it is an mRNA) or forms a 'structural' RNA, such as a transfer RNA (tRNA) or ribosomal RNA (rRNA) molecule.

5. Aminoacyl tRNA synthetase - Wikipedia

   en.wikipedia.org/wiki/Aminoacyl_tRNA_synthetase

   The synthetase first binds ATP and the corresponding amino acid (or its precursor) to form an aminoacyl-adenylate, releasing inorganic pyrophosphate (PPi).The adenylate-aaRS complex then binds the appropriate tRNA molecule's D arm, and the amino acid is transferred from the aa-AMP to either the 2'- or the 3'-OH of the last tRNA nucleotide (A76) at the 3'-end.

6. Telomerase RNA component - Wikipedia

   en.wikipedia.org/wiki/Telomerase_RNA_component

   Telomerase RNA component, also known as TR, TER or TERC, is an ncRNA found in eukaryotes that is a component of telomerase, the enzyme used to extend telomeres. [ 3 ] [ 4 ] TERC serves as a template for telomere replication ( reverse transcription ) by telomerase.

7. Telomerase - Wikipedia

   en.wikipedia.org/wiki/Telomerase

   Once recruited, the RNase L creates a single cleavage in the RNA (D) and causes dissociation of the RNA sequence. Another independent approach is to use oligoadenylated anti-telomerase antisense oligonucleotides and ribozymes to target telomerase RNA, leading to the dissociation of the RNA and to apoptosis (Figure 5). The fast induction of ...