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2,4-Dichlorophenoxyacetic acid is an organic compound with the chemical formula Cl 2 C 6 H 3 OCH 2 CO 2 H.It is usually referred to by its ISO common name 2,4-D. [4] It is a systemic herbicide that kills most broadleaf weeds by causing uncontrolled growth, but most grasses such as cereals, lawn turf, and grassland are relatively unaffected.
Its active metabolite, 2,4-D, inhibits growth at the tips of stems and roots. It is classified in toxicity class III. It shows some evidence of toxicity to dogs and cats, such as changes in body weight and reduced numbers of offspring, when fed 25-80 milligrams per kilogram of body weight for prolonged periods. Tests of carcinogenicity in this ...
Ethylene glycol, antifreeze, is extremely toxic to dogs. It has a sweet taste and thus dogs will drink it. As little as 2 1/2 tablespoons can kill a medium-sized dog in 2–3 days. This type of poisoning is often fatal as dog owners do not know their pet has ingested the antifreeze. De-icing fluids can also contain ethylene glycol.
Toxicity occurs through overdosage with an appropriate product or use of an agricultural product. Signs for both include hypersalivation, vomiting, lethargy, tremors, difficulty walking, weakness, and death. [174] Chocolate is a common cause of poisoning in dogs. The toxic principles in chocolate are theobromine and caffeine.
Pyriproxyfen has low acute toxicity. [11] According to WHO and FAO , at elevated doses exceeding 5000 mg/kg of body weight , pyriproxyfen affects the liver in mice, rats and dogs. [ 12 ] It also changes cholesterol levels, and may cause modest anemia at high doses.
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Form-2',4'-xylidide and 4-amino- meta-toluic acid account only for 2% of the total excretion. [20] In insects different metabolites are formed. N-methyl- N'-(2,4-xylyl)formamidine, Form-2,4-xylidine and 4-Amino-meta-toluic acid occur, but in addition several unidentified metabolites were detected, too. [21] Figure 4; Amitraz Metabolism in Plants
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