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  2. What Does Viagra Actually Do to Your "Intimate" Experience? - AOL

    www.aol.com/does-viagra-actually-intimate...

    For example, a small study of 20 people that looked into Viagra’s effect on refractory time found that a standard 100mg dose of sildenafil citrate reduced the average male post-intimacy recovery ...

  3. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

    www.aol.com/viagra-treats-side-effects-plus...

    Sildenafil’s ability to increase blood flow makes the medication useful for managing other conditions. Some sources suggest Viagra might make you last longer in bed, and others say it’s good ...

  4. 5 Must-Know Tips Before Taking Sildenafil 100mg - AOL

    www.aol.com/5-must-know-tips-taking-105700758.html

    Sildenafil usually takes about a half hour to start working, but for optimal results, take your prescribed dose of sildenafil an hour before the time you plan to get intimate. Avoid high-fat meals ...

  5. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [ 4 ] [ 8 ] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon . [ 9 ]

  6. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) typically start working within 30 to 60 minutes, while avanafil (Stendra) works within 15 to 30 minutes. As with most prescription ...

  7. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  8. Is Sildenafil Safe for This Common Male Problem? - AOL

    www.aol.com/lifestyle/sildenafil-safe-common...

    Sildenafil is most commonly prescribed to be taken one time per day in doses between 25 and 100 mg for ED. Your healthcare provider will determine the best dosage for you based on a number of factors.

  9. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Sildenafil was initially introduced for clinical trial in 1989. It was the result of extensive research on chemical agents targeting PDE5 that could be effective in treatment of coronary heart disease. [22] Sildenafil did not prove effective for coronary heart disease but an interesting side effect was discovered, a penile erection.

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