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Other side effects include paralysis, resulting in the inability to breathe. [9] If used during pregnancy it may cause permanent deafness in the baby. [9] [1] Amikacin works by blocking the function of the bacteria's 30S ribosomal subunit, making it unable to produce proteins. [9] Amikacin was patented in 1971, and came into commercial use in 1976.
Side effects from intra-articular administration can include joint pain, swelling, lameness, and, rarely, infection of the joint. Intramuscular injection can cause dose-dependent inflammation and bleeding, since PSGAG is an analogue of the anticoagulant heparin. [4] In dogs, this may manifest as bleeding from the nose or as bloody stools. [7]
Streptomycin was the first effective drug in the treatment of tuberculosis, though the role of aminoglycosides such as streptomycin and amikacin has been eclipsed (because of their toxicity and inconvenient route of administration) except for multiple-drug-resistant strains.
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Serious side effects include ringing in the ears or loss of hearing, toxicity to kidneys, and allergic reactions to the drug. [11] Ototoxicity is a common quality among aminoglycosides, and its rate of incidence in kanamycin is around 3-10%. [12] Other side effects include: [9] Gastrointestinal effects Nausea, vomiting, diarrhea ...
These side effects are generally mild and last no more than a few days at most. Rarely, nerves or blood vessels around the injection site can be damaged, resulting in severe pain or paralysis. If proper technique is not followed, intramuscular injections can result in localized infections such as abscesses and gangrene. While historically ...
Related: Benadryl for Dogs: Side Effects of Long-Term Use. ... (LD50) at 24 to 30 mg per kilogram when given by IV. The LD50 is when half the dogs die at that dose, so the toxic dose may be a lot ...
Long-Term Side Effects of Parvo. ... No boosters need to be given for about 3 years after this. ... Nutrient digestibility and fecal characteristics, microbiota, and metabolites in dogs fed human ...
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