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  2. Obstructive lung disease - Wikipedia

    en.wikipedia.org/wiki/Obstructive_lung_disease

    The most common cause of COPD is cigarette smoking. COPD is a gradually progressive condition and usually only develops after about 20 pack-years of smoking. COPD may also be caused by breathing in other particles and gases. [citation needed] The diagnosis of COPD is established through spirometry although other pulmonary function tests can be ...

  3. Bronchiectasis - Wikipedia

    en.wikipedia.org/wiki/Bronchiectasis

    It is caused by mutations in the CFTR protein, a chloride channel expressed in epithelial cells. [28] Lung disease results from clogging of the airways due to mucus build-up, decreased mucociliary clearance, and resulting inflammation. [30] In later stages, changes to the structure of the lung, such as bronchiectasis, occur.

  4. Effect of oxygen on chronic obstructive pulmonary disease

    en.wikipedia.org/wiki/Effect_of_oxygen_on...

    Many people with chronic obstructive pulmonary disease have a low partial pressure of oxygen in the blood and high partial pressure of carbon dioxide.Treatment with supplemental oxygen may improve their well-being; alternatively, in some this can lead to the adverse effect of elevating the carbon dioxide content in the blood (hypercapnia) to levels that may become toxic.

  5. Acute exacerbation of chronic obstructive pulmonary disease

    en.wikipedia.org/wiki/Acute_exacerbation_of...

    High flow oxygen may be harmful in those with an acute exacerbation of COPD. In the prehospital environment those given high flow O 2 rather than titrating their O 2 saturations to 88% to 92% had worse outcomes. [14] In specific circumstances high flow oxygen however can be beneficial. [15] Antibiotics and steroids appear useful in mild to ...

  6. Respiratory disease - Wikipedia

    en.wikipedia.org/wiki/Respiratory_disease

    Asthma, chronic bronchitis, bronchiectasis and chronic obstructive pulmonary disease (COPD) are all obstructive lung diseases characterised by airway obstruction.This limits the amount of air that is able to enter alveoli because of constriction of the bronchial tree, due to inflammation.

  7. Chronic obstructive pulmonary disease - Wikipedia

    en.wikipedia.org/wiki/Chronic_obstructive...

    Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...

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