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A 2004 statement by the European Society for Paediatric Endocrinology and the Lawson Wilkins Pediatric Endocrine Society (for children) uses slightly different cutoffs, where mild DKA is defined by pH 7.20–7.30 (bicarbonate 10–15 mmol/L), moderate DKA by pH 7.1–7.2 (bicarbonate 5–10) and severe DKA by pH<7.1 (bicarbonate below 5). [31]
DKA is a serious complication which is particularly common in children under five years of age and can lead to cerebral edema, coma, and death. [ 9 ] A 2013 publication also stated that children who develop T1D while enrolled in TEDDY are diagnosed sooner after the onset of the disease than those not in the study.
The log diagnostic odds ratio is sometimes used in meta-analyses of diagnostic test accuracy studies due to its simplicity (being approximately normally distributed). [ 4 ] Traditional meta-analytic techniques such as inverse-variance weighting can be used to combine log diagnostic odds ratios computed from a number of data sources to produce ...
Statistical tests are used to test the fit between a hypothesis and the data. [ 1 ] [ 2 ] Choosing the right statistical test is not a trivial task. [ 1 ] The choice of the test depends on many properties of the research question.
The one-sample test statistic, , for Kuiper's test is defined as follows. Let F be the continuous cumulative distribution function which is to be the null hypothesis . Denote by F n the empirical distribution function for n independent and identically distributed (i.i.d.) observations X i , which is defined as
A test statistic shares some of the same qualities of a descriptive statistic, and many statistics can be used as both test statistics and descriptive statistics. However, a test statistic is specifically intended for use in statistical testing, whereas the main quality of a descriptive statistic is that it is easily interpretable. Some ...
The procedure is to take the child's weight in pounds, divide by 150 lb, and multiply the fractional result by the adult dose to find the equivalent child dosage.For example, if an adult dose of medication calls for 30 mg and the child weighs 30 lb, divide the weight by 150 (30/150) to obtain 1/5 and multiply 1/5 times 30 mg to get 6 mg.
Student's t-test is a statistical test used to test whether the difference between the response of two groups is statistically significant or not. It is any statistical hypothesis test in which the test statistic follows a Student's t -distribution under the null hypothesis .