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CA-125 was initially detected using the murine monoclonal antibody designated OC125. Robert Bast , Robert Knapp and their research team first isolated this monoclonal antibody in 1981. [ 28 ] The protein was named "cancer antigen 125" because OC125 was the 125th antibody produced against the ovarian cancer cell line that was being studied.
CA-125: Mainly ovarian cancer, [12] but may also be elevated in for example endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer. [13] Calcitonin: medullary thyroid carcinoma [14] Calretinin: mesothelioma, sex cord-gonadal stromal tumor, adrenocortical carcinoma, synovial sarcoma [8] Carcinoembryonic ...
The one biomarker that has been in use over the last 20 years is CA-125. [121] A 2016 review found that this biomarker was present in those with symptoms of endometriosis; and, once ovarian cancer has been ruled out, a positive CA-125 may confirm the diagnosis. [122] Its performance in ruling out endometriosis is low. [122]
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. ...
TAG-72 is a tumor marker measured with radioimmunoassays like CA 72-4, which uses the monoclonal antibodies indium (111 In) satumomab pendetide and iodine (125 I) ...
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[148]: 125 The Pew Research Center's study of black and white old people found that 62% of those in ages 65–74 and 70% in ages 75+ asserted that religion was "very important" to them. For all 65+ people, more women (76%) than men (53%) and more blacks (87%) than whites (63%) consider religion "very important" to them.