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Transverse myelitis (TM) is a rare neurological condition wherein the spinal cord is inflamed.The adjective transverse implies that the spinal inflammation extends horizontally throughout the cross section of the spinal cord; [1] the terms partial transverse myelitis and partial myelitis are sometimes used to specify inflammation that affects only part of the width of the spinal cord. [1]
Millard criteria (Rule of 10) is a set of rules, which is to be fulfilled for undertaking elective surgery for children, and mostly used for reference in cleft lip surgery. The criteria includes these prerequisites: [ 1 ] [ 2 ]
These cytokines mediate the activation of type 2 T helper cells (T h 2 cells), type 2 innate lymphoid cells (ILC2 cells), and dendritic cells. T h 2 cells and ILC2 cells secrete IL-4, IL-5 and IL-13. [1] [3] IL-4 further drives CD4+ T cell differentiation towards the T h 2 subtype and induces isotype switching to IgE in B cells.
Most jewelers agree that the "three month's salary" rule for an engagement ring no longer applies. This guideline would indicate that if you make $100,000 a year -- barely enough to afford a house ...
During the first 3 months of pregnancy, the main form of hemoglobin in the embryo/fetus is embryonic hemoglobin, which has 3 variants depending on the types of subunits it contains. The production of hemoglobin F starts from week 6, but it's only from 3 months onwards that it becomes the main type found in fetal red blood cells. [4]
In a screen to identify differentially expressed molecules between Th1 and Th2 cells, Vijay Kuchroo and colleagues first described HAVCR2/TIM-3 in 2002. [5] Kuchroo was the first to characterize the inhibitory function of TIM-3 and its role in inhibiting T cell responses in both autoimmunity and cancer. [11]
CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). [1] It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains.
The typical normal human fetal cell will divide between 50 and 70 times before experiencing senescence. As the cell divides, the telomeres on the ends of chromosomes shorten. The Hayflick limit is the limit on cell replication imposed by the shortening of telomeres with each division. This end stage is known as cellular senescence.