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Arteriosclerosis, literally meaning "hardening of the arteries", is an umbrella term for a vascular disorder characterized by abnormal thickening, hardening, and loss of elasticity [3] of the walls of arteries; [4] this process gradually restricts the blood flow to one's organs and tissues and can lead to severe health risks brought on by atherosclerosis, which is a specific form of ...
Atherosclerosis [a] is a pattern of the disease arteriosclerosis, [8] characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types and is driven by elevated levels of cholesterol in the blood. [ 9 ]
As previously mentioned, the most common etiology of peripheral artery disease, especially in patients over 40 years old, is atherosclerosis. [19] Atherosclerosis is a narrowing of the arteries caused by lipid or fat buildup and calcium deposition in the wall of the affected arteries.
Atherosclerosis is characterized by the build-up of plaque inside your blood vessels. It can lead to stenosis, which is a narrowing of your artery walls. Plaque is a fatty substance made up of:
Arterial occlusion can be classified into three types based on etiology: embolism, thrombosis, and atherosclerosis. These three types of occlusion underlie various common conditions, including coronary artery disease , [ 4 ] peripheral artery disease , [ 5 ] and pulmonary embolism , [ 6 ] which may be prevented by lowering risk factors.
Image depicting atherosclerosis. Coronary occlusion is caused by the buildup of fats, cholesterol and other substances in and on the walls of the hearts arteries. [6] As plaque builds up, the arteries narrow. [7] Plaque often starts building up during childhood and is heavily influence by genetics, but also lifestyle and high blood cholesterol. [7]
Atherosclerosis narrows blood vessels in the brain, resulting in decreased cerebral perfusion. Other risk factors that contribute to stroke include smoking and diabetes. [ 6 ] Narrowed cerebral arteries can lead to ischemic stroke , but continually elevated blood pressure can also cause tearing of vessels, leading to a hemorrhagic stroke.
Atherosclerosis is a hardening of an artery specifically due to an atheromatous plaque. The term atherogenic is used for substances or processes that cause atherosclerosis. Micrograph showing hyaline arteriolosclerosis in the kidney. PAS stain.
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