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Endochondral ossification is responsible for development of most bones including long and short bones, [4] the bones of the axial (ribs and vertebrae) and the appendicular skeleton (e.g. upper and lower limbs), [5] the bones of the skull base (including the ethmoid and sphenoid bones) [6] and the medial end of the clavicle. [7]
Diameter of canaliculi in human bone is approximately 200 to 900 nm. [1] In bovine tibia diameter of canaliculi was found to vary from 155 to 844 nm (average 426 nm). [ 2 ] In mice humeri it varies from 80 to 710 nm (average 259 nm), while diameter of osteocytic processes varies from 50 to 410 nm (average 104 nm).
Gross anatomy (also called topographical anatomy, regional anatomy, or anthropotomy) is the study of anatomical structures that can be seen by the naked eye. [1] Microscopic anatomy is the study of minute anatomical structures assisted with microscopes , which includes histology (the study of the organization of tissues), [ 1 ] and cytology ...
In an ordinary microscopic section, viewed by transmitted light, they appear as fusiform opaque spots. Each lacuna is occupied during life by a branched cell, termed an osteocyte, bone-cell or bone-corpuscle. Lacunae are connected to one another by small canals called canaliculi. A lacuna never contains more than one osteocyte.
Diagram of a typical long bone showing both cortical (compact) and cancellous (spongy) bone. Haversian canals [i] (sometimes canals of Havers, osteonic canals or central canals) are a series of microscopic tubes in the outermost region of bone called cortical bone. They allow blood vessels and nerves to travel through them to supply the osteocytes.
Histologic specimen being placed on the stage of an optical microscope Human lung tissue stained with hematoxylin and eosin as seen under a microscope. Histology, [help 1] also known as microscopic anatomy or microanatomy, [1] is the branch of biology that studies the microscopic anatomy of biological tissues.
Hyaline cartilage is the most common kind of cartilage in the human body. [2] It is primarily composed of type II collagen and proteoglycans. [2] Hyaline cartilage is located in the trachea, nose, epiphyseal plate, sternum, and ribs.
Diagram showing stages of endochondral ossification. Endochondral ossification is the formation of long bones and other bones. This requires a hyaline cartilage precursor. There are two centers of ossification for endochondral ossification. The primary center. In long bones, bone tissue first appears in the diaphysis (middle of shaft).
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