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4837 18113 Ensembl ENSG00000166741 ENSMUSG00000032271 UniProt P40261 O55239 RefSeq (mRNA) NM_006169 NM_001311062 NM_010924 RefSeq (protein) NP_006160 NP_001358974 NP_001358975 NP_001358976 NP_001297991 NP_035054 Location (UCSC) Chr 11: 114.26 – 114.31 Mb Chr 9: 48.5 – 48.52 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Nicotinamide N-methyltransferase (NNMT) is an enzyme that ...
Sirtuin 1, also known as NAD-dependent deacetylase sirtuin-1, is a protein that in humans is encoded by the SIRT1 gene. [5] [6] [7]SIRT1 stands for sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), referring to the fact that its sirtuin homolog (biological equivalent across species) in yeast (Saccharomyces cerevisiae) is Sir2.
[4] [5] [6] The name Sir2 comes from the yeast gene 'silent mating-type information regulation 2', [7] the gene responsible for cellular regulation in yeast. From in vitro studies, sirtuins were thought to be implicated in influencing cellular processes like aging , transcription , apoptosis , inflammation [ 8 ] and stress resistance, as well ...
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A less casual, earlier type of slip-on is made with side goring (sometimes called a dress loafer). [4] Made in the same shape as lace-up Oxfords, but lacking the laces, these shoes have elasticated inserts on the side which allow the shoe to be easily removed but remain snug when worn. This cut has its greatest popularity in Britain. [5]
UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature.
In the 1980s and 1990s, clogs based on Swedish clogs returned in fashion for women. Platform clogs or sandals, often raised as high as 6 or even 8 inches right through between sole and insole, were worn in many western countries. The large mid layer was often made of solid cork, although some were merely of plastic with a cork covering.
The rhaḯdia (ῥαΐδια) extended the straps of the sandal up the calf. [8] Some Greek sandals—like the women's tyrrēniká (τυρρηνικά)—employed wooden soles. [8] The effeminate baxea (πάξεια, páxeia) was usually made of willow leaves, twigs, or fibers and was associated with comic actors and philosophers. [9]
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