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Manipulation under anesthesia (MUA) or fibrosis release procedures [1] is a noninvasive procedure to treat chronic pain which has been unmanageable by other methods. MUA is designed not only to relieve pain, but also to break up excessive scar tissue.
Physiologically, fibrosis acts to deposit connective tissue, which can interfere with or totally inhibit the normal architecture and function of the underlying organ or tissue. Fibrosis can be used to describe the pathological state of excess deposition of fibrous tissue, as well as the process of connective tissue deposition in healing. [4]
Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
Fibromuscular tissue is made up of fibrous tissue and muscular tissue. New vascularised connective tissue that forms in the process of wound healing is termed granulation tissue. [13] All of the special connective tissue types have been included as a subset of fascia in the fascial system, with blood and lymph classed as liquid fascia. [14] [15]
Arthrofibrosis (from Greek: arthro-joint, fibrosis – scar tissue formation) has been described in most joints like knee, hip, ankle, foot joints, shoulder (frozen shoulder, adhesive capsulitis), elbow (stiff elbow), wrist, hand joints as well as spinal vertebrae. [1] [2] It can occur after injury or surgery or may arise without an obvious ...
Myocardial scarring is the accumulation of fibrous tissue resulting after some form of trauma to the cardiac tissue. [1] [2] Fibrosis is the formation of excess tissue in replacement of necrotic or extensively damaged tissue. Fibrosis in the heart is often hard to detect because fibromas, scar tissue or small tumors formed in one cell line, are ...
Scar tissue is composed of the same protein as the tissue that it replaces, but the fiber composition of the protein is different; instead of a random basketweave formation of the collagen fibers found in normal tissue, in fibrosis the collagen cross-links and forms a pronounced alignment in a single direction. [1]
The fibroblasts within the granulation tissue develop into chondroblasts which also form hyaline cartilage. These two new tissues grow in size until they unite with each other. These processes culminate in a new mass of heterogeneous tissue known as a fracture callus. [citation needed] Callus formation peaks at day 14 of fracture. [4]